Opuntia ficus indica
Prickly pear, Nopal
Plant originating from Mexico, present in the Mediterranean basin as far as Australia
EXTRACT FROM THE PRICKLY PEAR DEVELOPED BY OUR LABORATORIES: TEX-OE, OPUNTIA MESOCARP EXTRACT® (Texinfine Opuntia extract)
The natural protection of the prickly pear, contained in the extract : TEX-OE, Opuntia mesocarp extract®.
The prickly pear is the fruit produced by the prickly pear, a plant of the Cactaceae family. This edible fruit, being covered with small and fine thorns, is meticulously cleaned to recover the precious mesocarp, part of the pericarp. Opuntia ficus indica is one of the few fleshy fruit plants that can withstand direct and permanent exposure to sunlight with significant temperature variations. In order to resist such environmental conditions, this fruit is able to synthesize stress proteins called Heat Shock Proteins (HSP). These proteins, which are highly preserved during evolution, are found in practically all living organisms, from bacteria to humans and thus ensure the protection of cells exposed to all types of cellular stress (variations in temperature, pressure or altitude, radiation, injuries, intensive sports training, microbial attacks, toxic agents or bioerosion) likely to permanently alter the conformation of proteins.
For more information on this subject
- Briffa, Michelle & Ghio, Stephanie & Neuner, Johanna & Gauci, Alison & Cacciottolo, Rebecca & Marchal, Christelle & Caruana, Mario & Cullin, Christophe & Vassallo, Neville & J. Cauchi, Ruben. (2016). Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies. Neuroscience Letters. 638. 10.1016/d. neulet.2016.11.058.
- Baluci C. A., Saliba C., Gutierrez G., Collie A. Agius C. (2005). Effects of Tex-OE® pre-conditioning on cognitive on cognitive outcome after acute alcohol consumption; New Clinical Drug Evaluation Unit (NCDEU) Annual Meeting, Boca Raton, Florida USA.
- Caroline Jolly, Richard I. Morimoto, Role of the Heat Shock Response and Molecular Chaperones in Oncogenesis and Cell Death, JNCI: Journal of the National Cancer Institute, Volume 92, Issue 19, 4 October 2000, Pages 1564-1572, https://doi.org/10.1093/jnci/92.19.1564
- Brahmi, D., Bouaziz, C., Ayed, Y., et al. Chemopreventive effect of cactus Opuntia ficus indica on oxidative stress and genotoxicity of aflatoxin B1. (2011). Nutr Metab (Lond) 8: 73. https://doi.org/10.1186/1743-7075-8-73.
- Galati E.M., Mondello M.R., Lauriano E.R.; Taviano M.F; Galluzzo M.; Miceli N. (2005). Opuntia ficus indica (L) Mill. Fruit juice protects liver from Carbon Tetrachloride- induced injury; Phytother Res. 2005 Sep;19(9):796-800.
- Gutierrez G., Serrar M., Viornery L,. Norton J., (2004). Biologically active substances, method for obtaining and compositions containing them US6737086B2.
- Grimaud J-A,. Gutierrez G., Serrar M., (2007). Novel proline-derivative based cosmetological and/or dermatological compositions and uses thereof. WO2007072178A1.
- G. Choo, K. Elnomrosy, M. Brincat, G. Gutierrez (2000). The effect of subjecting sperm to stress before cryopreservation on post-thaw motility. International Journal of Gynaecology & Obstetrics. Volume 70, Issue S2. Pages B74-B74 https://doi.org/10.1016/S0020-7292(00)85145-0.
- R. Cali-Corleo; G. Gutierrez; C. Saliba; M. Serrar; A. Marroni; M. Brincat; MCormary. (1999). Heat Shock Protein 72 rises following a diving stress and this rise is accelerated following preconditioning using TEX-OE®; British Hyperbaric Association, Hull.
- Somers, Daryl & W. Giroux, Randal & Gary Filion, W. (2011). The expression of temperature-stress proteins in a desert cactus (Opuntia ficus indica). Genome. 34. 940-943. 10.1139/g91-145.
- Weise J., McPherson S., Odden M.C., Shlipak M.G. (2004). Effect of Opuntia ficus indica on Symptoms of the Alcohol Hangover; Arch Intern Med 2004; 164: 1334-1340.